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Anti -AKAP-associated Sperm Protein (ASP, ROPN1L, Ropporin-1 Like, AKAP-associated Sperm Protein)
Anti -AKAP-associated Sperm Protein (ASP, ROPN1L, Ropporin-1 Like, AKAP-associated Sperm
Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| AKAPs act as scaffolding proteins co-ordinating phosphotase:kinase signaling at the cytoskeleton. They interact with PKAs and anchor them to specific sub-cellular compartments and participate in multiple cellular processes including growth, metabolism and differentiation. ASP, a 26KD protein, is a novel AKAP-interacting protein. It interacts with the amphipathic helix of AKAP3 and facilitates AKAP3-PKA interactions. It consists of a conserved N-terminal AKAP-binding domain and a central cysteine-rich Fz domain. It is specifically expressed in the sperms and might play a significant role in sperm motily and also facilitate cytoskeletal reorganization during spermiogenesis. | | | Catalog # | A1105-75A | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa58-73(KDRMEMPTATQKTDTG) and 176-191(ARLDSDVSPLETESYL) of human ASP. | | Specificity | Recognizes human AKAP-associated sperm protein (ASP). Species sequence homology: mouse, bovine, chimpanzee, canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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