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You are here:Home » Antibodies » Antibodies-Signal Transduction » Anti -AKAP-associated Sperm Protein (ASP, ROPN1L, Ropporin-1 Like, AKAP-associated Sperm Protein)

Anti -AKAP-associated Sperm Protein (ASP, ROPN1L, Ropporin-1 Like, AKAP-associated Sperm


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
AKAPs act as scaffolding proteins co-ordinating phosphotase:kinase signaling at the cytoskeleton. They interact with PKAs and anchor them to specific sub-cellular compartments and participate in multiple cellular processes including growth, metabolism and differentiation. ASP, a 26KD protein, is a novel AKAP-interacting protein. It interacts with the amphipathic helix of AKAP3 and facilitates AKAP3-PKA interactions. It consists of a conserved N-terminal AKAP-binding domain and a central cysteine-rich Fz domain. It is specifically expressed in the sperms and might play a significant role in sperm motily and also facilitate cytoskeletal reorganization during spermiogenesis.
Catalog #A1105-75A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa58-73(KDRMEMPTATQKTDTG) and 176-191(ARLDSDVSPLETESYL) of human ASP.
SpecificityRecognizes human AKAP-associated sperm protein (ASP). Species sequence homology: mouse, bovine, chimpanzee, canine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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