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You are here:Home » Antibodies » Antibodies-Protein Kinases » Anti -AKT, pan, NT (Rac PKa, PKBa)

Anti -AKT, pan, NT (Rac PKa, PKBa)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The serine-threonine kinase Akt, also known as protein kinase B (PKB), is an important effector for phosphatidylinositol 3-kinase signaling, initiated by numerous growth factors and hormones. Three mammalian isoforms (Akt1/PKBa, Akt2/PKBb, and Akt3/PKBg) have been cloned. Akt2 and Akt3 have 81% and 83% homology in aa sequences with Akt1, respectively. Numerous studies have revealed that the expression pattern of Akt1 and Akt2 is ubiquitous, whereas Akt3 is expressed predominantly in the brain, heart, and kidneys. Akt has a pivotal role in cell cycle progression, inhibition of apoptosis and cell growth.
Catalog #A1124-12J
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa70 of human Akt2.
SpecificityRecognizes human Akt1, Akt2 and Akt3. Species Crossreactivity: mouse, rat, bovine and frog.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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