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Anti -AKT2, CT (RAC-beta Serine/Threonine-protein Kinase, Protein Kinase Akt-2, Protein Kinase B beta, PKB beta, RAC-PK-beta)
Anti -AKT2, CT (RAC-beta Serine/Threonine-protein Kinase, Protein Kinase Akt-2, Protein
Kinase B beta, PKB beta, RAC-PK-beta)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| The serine-threonine kinase Akt, also known as protein kinase B (PKB), is an important effector for phosphatidylinositol 3-kinase signaling initiated by numerous growth factors and hormones. Akt2/PKB beta, one of three known mammalian isoforms of Akt/PKB, has been demonstrated recently to be required for at least some of the metabolic actions. Over expression of exogenous Akt enhances cell survival by dramatically reducing apoptosis and transfection of dominant negative mutant kinase constructs (kinase-dead) inhibits survival of neurons promoted by IGF-1. Akt2 is also expressed in human carcinoma cell lines and primary tumors. | | | Catalog # | A1125-28P | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 0.1-1ug/ml | | Western Blot: 0.5-2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to region surrounding Threonine 308 from AKT2. | | Specificity | Recognizes human AKT2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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