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You are here:Home » Antibodies » Abs to Neuroscience » Anti -Alarin (del/E3, Galanin-like Peptide, GALP)

Anti -Alarin (del/E3, Galanin-like Peptide, GALP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH IF
Alarin is a hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2, and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. Isoform 2 exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2 (By similarity). Cleavage of the signal peptide generates a peptide of 25 amino acids, termed alarin because of the N-terminal alanine and the C-terminal serine. Involved in ganglionic differentiation in neuroblastic tumor tissues.
Catalog #A1232-21A
ApplicationsSuitable for use in Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:200
Immunohistochemistry (formalin-fixed paraffin): 1:500 (PAP or ABC) 1 hour at RT. No pretreatment required. Recommended Counterstained Hematoxylin.
Optimal dilutions to be determined by the researcher.
Recommended Secondary AntibodyI1904-43: IgG, X-Adsorbed (Biotin) Pab GtxRb
I1904-40E: IgG, H&L (Biotin) Pab
I1904-46P: IgG, H&L (Biotin) GtxRb
Positive ControlMouse/Rat Brain Tissue
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 100ul sterile dH2O.
PuritySerum
ImmunogenSynthetic peptide corresponding to rat Alarin.
SpecificityRecognizes rat Alarin. Species crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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