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You are here:Home » Antibodies » Abs to Enzymes, Dehydrogenase » Anti -Aldehyde Dehydrogenase 1A1 (Aldh1a1, Acetaldehyde Dehydrogenase 1, AHD2, ALDC, Aldehyde Dehydrogenase 1 Soluble, Aldehyde Dehydrogenase 1A1, Aldehyde Dehydrogenase Cytosolic, Aldehyde Dehydrogenase Liver (cytosolic), MGC2318, PUMB1, RALDH 1, RalDH1, Retin

Anti -Aldehyde Dehydrogenase 1A1 (Aldh1a1, Acetaldehyde Dehydrogenase 1, AHD2, ALDC,
Aldehyde Dehydrogenase 1 Soluble, Aldehyde Dehydrogenase 1A1, Aldehyde Dehydrogenase
Cytosolic, Aldehyde Dehydrogenase Liver (cytosolic), MGC2318, PUMB1, RALDH 1, RalDH1,
Retin

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Catalog #A1334-33G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.03-0.1ug/ml
Optimal dilutions to be determined by the researcher.
Titer1:16,000 (by peptide ELISA)
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acids near the C-terminus of human ALDH1A1
SpecificityRecognizes human ALDH1A1 at ~55kD in human liver lysates (calculated MW of 54.9kD according to NP_000680.2). This antibody may cross-react with ALDH1A2 (GeneID 8854) with one residue difference from this design and with ALDH2 (GeneID 217) with two residues difference from this design. Species Crossreactivity: Canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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