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You are here:Home » Antibodies » Abs to Enzymes, Dehydrogenase » Anti -Aldehyde Dehydrogenase Family 3, Member A2 (Aldh3A2, Aldehyde dehydrogenase, microsomal, Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, ALDH10, DKFZp686E23276, FALDH, Fatty aldehyde dehydrogenase, FLJ20851, SLS)

Anti -Aldehyde Dehydrogenase Family 3, Member A2 (Aldh3A2, Aldehyde dehydrogenase,
microsomal, Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, ALDH10,
DKFZp686E23276, FALDH, Fatty aldehyde dehydrogenase, FLJ20851, SLS)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism. At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.
Catalog #A1334-37D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlMouse Liver Tissue Lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 14aa from near the carboxy terminus of the human Aldh3A2.
SpecificityRecognizes human Aldh3A2. Species Crossreactivity: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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