Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Prostaglandins » Anti -Aldo-Keto Reductase Family 1 Member C3 (AKR1C3, DD3, HAKRB, HAKRe, HA1753, HSD17B5, hluPGFS, KIAA0119, 3-alpha Hydroxysteroid Dehydrogenase Type II, Prostaglandin F Synthase, Dihydrodiol Dehydrogenase 3, Chlordecone Reductase Homolog, Hydroxysteroid (17-b

Anti -Aldo-Keto Reductase Family 1 Member C3 (AKR1C3, DD3, HAKRB, HAKRe, HA1753, HSD17B5,
hluPGFS, KIAA0119, 3-alpha Hydroxysteroid Dehydrogenase Type II, Prostaglandin F Synthase,
Dihydrodiol Dehydrogenase 3, Chlordecone Reductase Homolog, Hydroxysteroid (17-b

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Catalog #A1334-70O
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32000
Western Blot: 0.01-0.1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human AKR1C3.
SpecificityRecognizes human AKR1C3 at ~35kD in human liver and human breast lysates (calculated MW of 36.9kD according to NP_003730).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links