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You are here:Home » Antibodies » Abs to Prostaglandins » Anti -Aldo-Keto Reductase Family 1 Member C3, CT (AKR1C3, DD3, HAKRB, HAKRe, HA1753, HSD17B5, hluPGFS, KIAA0119, 3-alpha Hydroxysteroid Dehydrogenase Type II, Prostaglandin F Synthase, Dihydrodiol Dehydrogenase 3, Chlordecone Reductase Homolog, Hydroxysteroid (

Anti -Aldo-Keto Reductase Family 1 Member C3, CT (AKR1C3, DD3, HAKRB, HAKRe, HA1753,
HSD17B5, hluPGFS, KIAA0119, 3-alpha Hydroxysteroid Dehydrogenase Type II, Prostaglandin F
Synthase, Dihydrodiol Dehydrogenase 3, Chlordecone Reductase Homolog, Hydroxysteroid (

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Catalog #A1334-70P1
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 1:32,000 & 0.01-0.1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to CFASHPNYPYSDEY from the C-terminal of human AKR1C3.
SpecificityRecognizes human AKR1C3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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