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You are here:Home » Antibodies » Abs to Prostaglandins » Anti -Aldo-Keto Reductase Family 1 Member C3 (AKR1C3, DD3, HAKRB, HAKRe, HA1753, HSD17B5, hluPGFS, KIAA0119, 3-alpha Hydroxysteroid Dehydrogenase Type II, Prostaglandin F Synthase, Dihydrodiol Dehydrogenase 3, Chlordecone Reductase Homolog, Hydroxysteroid (17-b

Anti -Aldo-Keto Reductase Family 1 Member C3 (AKR1C3, DD3, HAKRB, HAKRe, HA1753, HSD17B5,
hluPGFS, KIAA0119, 3-alpha Hydroxysteroid Dehydrogenase Type II, Prostaglandin F Synthase,
Dihydrodiol Dehydrogenase 3, Chlordecone Reductase Homolog, Hydroxysteroid (17-b

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation.
Catalog #A1334-70Q
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.01-0.1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Breast lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to CFASHPNYPYSDEY, from the C-terminus of the protein sequence according to NP_003730.
SpecificityRecognizes human AKR1C3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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