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You are here:Home » Antibodies » Abs to Enzymes, Dehydrogenase » Anti -Aldo-Keto Reductase Family 1 Member C4 (AKR1C4, HGNC:387, 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581, 3-alpha Hydroxysteroid Dehydrogenase Type I, 3 alpha-Hydroxysteroid Dehydrogenase, 3-alpha-Hydroxysteroid Dehydrogenase Variant, Chlordecone Reduc

Anti -Aldo-Keto Reductase Family 1 Member C4 (AKR1C4, HGNC:387, 3-alpha-HSD, C11, CDR,
CHDR, DD4, HAKRA, MGC22581, 3-alpha Hydroxysteroid Dehydrogenase Type I, 3
alpha-Hydroxysteroid Dehydrogenase, 3-alpha-Hydroxysteroid Dehydrogenase Variant,
Chlordecone Reduc

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Catalog #A1334-70T
Positive Control Human Liver lysate
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, DPKYQRVELNDGH-C, representing the N Terminus of the human protein according to NP_001809.2.
SpecificitySpecies Crossreactivity: Human. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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