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You are here:Home » Antibodies » Abs to Enzymes, Reductase » Anti -Aldo-Keto Reductase Family 1 Member B10 (AKR1B10, Aldose Reductase-like, Aldose Reductase-related Protein, ALDRLn, ARL 1, ARL-1, hARP, HIS, HSI, MGC14103, Small Intestine Reductase, SI Reductase)

Anti -Aldo-Keto Reductase Family 1 Member B10 (AKR1B10, Aldose Reductase-like, Aldose
Reductase-related Protein, ALDRLn, ARL 1, ARL-1, hARP, HIS, HSI, MGC14103, Small Intestine
Reductase, SI Reductase)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
A 316aa protein, AKR1B10 is a highly efficient retinal reductase constituting the first cytosolic NADP (H)-dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications. It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma.
Catalog #A1334-70W2
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman, mouse or rat liver tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa100-200 of human AKR1B10 protein.
SpecificityRecognizes human AKR1B10. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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