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You are here:Home » Antibodies » Abs to Neuroscience » Anti -ALI1 (Amphoterin-induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, AMIGO2)

Anti -ALI1 (Amphoterin-induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in
Gastric Adenocarcinomas, DEGA, AMIGO2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.
Catalog #A1355-63B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa449-464 [TGDASADDRKAGKRVV] of mouse and rat Alivin 1.
SpecificityRecognizes mouse Alivin 1. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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