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You are here:Home » Antibodies » Abs to Apoptosis » Anti -ALIX (Apoptosis-linked Gene 2 Interacting Protein X, ALG-2-interacting Protein 1, AIP1, Dopamine Receptor Interacting Protein 4, DRIP4, HP95, KIAA1375, MGC17003, Programmed Cell Death 6 Interacting Protein, PDCD6 Interacting Protein, PDCD6IP)

Anti -ALIX (Apoptosis-linked Gene 2 Interacting Protein X, ALG-2-interacting Protein 1,
AIP1, Dopamine Receptor Interacting Protein 4, DRIP4, HP95, KIAA1375, MGC17003, Programmed
Cell Death 6 Interacting Protein, PDCD6 Interacting Protein, PDCD6IP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IF
Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. Predicted molecular weight approximately 96kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interact with multiple cellular Alix-binding partners that are involved in apoptotic induction, endosomal sorting, and endocytosis. Bro1 domain interacts with CHMP4b which is also involved in endosomal sorting.
Catalog #A1355-64D
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
HostMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to full-length human Alix.
SpecificityRecognizes human Alix. Species Crossreactivity: mouse and frog.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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