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Anti -Alsin, CT (ALS2, Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 6 Protein, Amyotrophic Lateral Sclerosis 2 Protein, ALS2CR6, KIAA1563)
Anti -Alsin, CT (ALS2, Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 6
Protein, Amyotrophic Lateral Sclerosis 2 Protein, ALS2CR6, KIAA1563)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E IH |
|
| ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. | | | Catalog # | A1362-85D | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:8000 | | Immunohistochemistry (Formalin-fixed, paraffin-embedded): 3.75ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | | Immunogen | Synthetic peptide corresponding to LKACYYQIQREKLN from the C-terminal of human ALS2. | | Specificity | Recognizes human ALS2. Species sequence homology: Canine, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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