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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -ATIC (Bifunctional Purine Biosynthesis Protein PURH, Phosphoribosylaminoimidazole carboxamide Formyltransferase, 5-aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase, AICAR Transformylase, IMP Cyclohydrolase, Inosinicase, IMP Synthetase, OK/SW-

Anti -ATIC (Bifunctional Purine Biosynthesis Protein PURH, Phosphoribosylaminoimidazole
carboxamide Formyltransferase, 5-aminoimidazole-4-Carboxamide Ribonucleotide
Formyltransferase, AICAR Transformylase, IMP Cyclohydrolase, Inosinicase, IMP Synthetase,
OK/SW-

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
ATIC (AICAR transformylase/IMP cyclohydrolase) belongs to the purH family, expressed in the cytoplasm, predicted molecular weight approximately 65kD. ATIC catalyzes the penultimate and final steps in the de novo purine nucleotide biosynthesis pathway. ATIC acts as a bifunctional enzyme catalyze the formation of FAICAR and IMP. AICA-ribosiduria is a recently discovered inherited metabolic disease caused by a defect in final steps of purine de novo biosynthesis.
Catalog #A1378-25C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 5-10ug/5ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
HostMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide AHTNLRLFHH conjugated to Ovalbumin.
SpecificityRecognizes ATIC. Species Crossreactivity: human, mouse, rat, frog and drosophila.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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