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Anti -ATIC (Bifunctional Purine Biosynthesis Protein PURH, Phosphoribosylaminoimidazole carboxamide Formyltransferase, 5-aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase, AICAR Transformylase, IMP Cyclohydrolase, Inosinicase, IMP Synthetase, OK/SW-
Anti -ATIC (Bifunctional Purine Biosynthesis Protein PURH, Phosphoribosylaminoimidazole
carboxamide Formyltransferase, 5-aminoimidazole-4-Carboxamide Ribonucleotide
Formyltransferase, AICAR Transformylase, IMP Cyclohydrolase, Inosinicase, IMP Synthetase,
OK/SW-
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B |
|
| ATIC (AICAR transformylase/IMP cyclohydrolase) belongs to the purH family, expressed in the cytoplasm, predicted molecular weight approximately 65kD. ATIC catalyzes the penultimate and final steps in the de novo purine nucleotide biosynthesis pathway. ATIC acts as a bifunctional enzyme catalyze the formation of FAICAR and IMP. AICA-ribosiduria is a recently discovered inherited metabolic disease caused by a defect in final steps of purine de novo biosynthesis. | | | Catalog # | A1378-25C | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 5-10ug/5ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Host | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide AHTNLRLFHH conjugated to Ovalbumin. | | Specificity | Recognizes ATIC. Species Crossreactivity: human, mouse, rat, frog and drosophila. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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