Naturally occurring amino acid; precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme. Antineoplastic (photosensitizer). 5-ALA is used in photodynamic therapy due to its properties as a photosensitizer, with applications in treatment of acne. 5-Aminolevulinic acid hydrochloride is used for visualisation of tumorous tissue in neurosurgical procedures enabling a reduction in the tumor residual volume and prolongation of progression-free survival in people with malignant gliomas. 5-ALA also has potential applications in diagnostic oncology in detection of bladder cancer
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