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Specifications

Clone Host Grade Applications Polyclonal Sheep Purified E

Amitriptyline is a tricyclic antidepressant (TCA). Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotonin-norepinephrine reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer side-effects. Tricyclic antidepressants are not considered addictive and have a low abuse potential, but suddenly discontinuing treatment may results in discontinuation syndrome and overdose is a main cause of death from prescription drugs. They have significant cardiovascular and neurological toxicity. Monitoring of TCA levels can help determine toxicity, monitor compliance and establish individual target concentrations.
Catalog #	A1382-02
Applications	Suitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
	ELISA: 2.5ug/ml
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Sheep
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity	Purified by caprylic acid and ammonium sulphate precipitation
Immunogen	Amitriptyline-BTG
Specificity	Recognizes Amitriptyline.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	Elavil, Tryptizol, Laroxyl, Sarotex, Lentizol