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You are here:Home » Antibodies » Abs to Drugs » Anti -Amodiaquine

Anti -Amodiaquine

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Amodiaquine is an antimalarial drug with effects very similar to those of chloroquine. Amodiaquine has been widely used to treat malaria. Due to reports of fatal adverse drug reactions, discontinuation or modification of its use has been suggested. Amodiaquine is a hapten of molecular weight 267.3g/mol.
Catalog #A1460
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:4000
Optimal dilutions to be determined by the researcher.
Hybridoma:
X63-Ag8.653. Female CF1 x Balb/c mice immunized i.p. with immunogen adsorbed onto Al(OH)3.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No6D10
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5M sodium chloride,15mM sodium azide.
PurityPurified by Protein A/G affinity chromatography from culture supernatant.
Immunogen4-amino-2(diethylaminomethyl)phenol coupled to S3.
SpecificityRecognizes the non-quinoline sidechain of amodiaquine. Reacts with amodiaquine and is able to distinguish from other antimalarial drugs. Can be used for quantitation of amodiaquine in human serum or plasma with a detection limit of approximately 2ng/ml.
Crossreactivity towards desethylchloroquine is ~1%. Crossreactivity towards desethylamodiaquine has not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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