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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E

Amodiaquine is an antimalarial drug with effects very similar to those of chloroquine. Amodiaquine has been widely used to treat malaria. Due to reports of fatal adverse drug reactions, discontinuation or modification of its use has been suggested. Amodiaquine is a hapten of molecular weight 267.3g/mol.
Catalog #	A1460
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilution	ELISA: 1:4000
	Optimal dilutions to be determined by the researcher.
	Hybridoma:
	X63-Ag8.653. Female CF1 x Balb/c mice immunized i.p. with immunogen adsorbed onto Al(OH)3.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2a,k
Clone No	6D10
Host	Mouse
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS, pH 7.2, 0.5M sodium chloride,15mM sodium azide.
Purity	Purified by Protein A/G affinity chromatography from culture supernatant.
Immunogen	4-amino-2(diethylaminomethyl)phenol coupled to S3.
Specificity	Recognizes the non-quinoline sidechain of amodiaquine. Reacts with amodiaquine and is able to distinguish from other antimalarial drugs. Can be used for quantitation of amodiaquine in human serum or plasma with a detection limit of approximately 2ng/ml.
Crossreactivity towards desethylchloroquine is ~1%. Crossreactivity towards desethylamodiaquine has not been tested.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.