Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Protein Kinases » Anti -AMP Activated Protein Kinase alpha2 (5'-AMP-activated Protein Kinase Catalytic Subunit alpha-2, AMPK alpha-2 Chain, AMPK Subunit alpha-2, AMPK a2, AMPK2, PRKAA2, PRKAA)

Anti -AMP Activated Protein Kinase alpha2 (5'-AMP-activated Protein Kinase Catalytic
Subunit alpha-2, AMPK alpha-2 Chain, AMPK Subunit alpha-2, AMPK a2, AMPK2, PRKAA2, PRKAA)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta- methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Catalog #A1475-02L
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
ELISA: 0.25ug/ml
Western Blot: 2.5-5ug/ml detects a band at ~62kD
Immunohistochemistry (FFPE): 5-25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography
ImmunogenSynthetic peptide corresponding to the C-terminal region of human PRKAA2 conjugated to KLH.
SpecificityRecognizes human PRKAA2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=2.7.11.1, Protein Kinase AMP-activated alpha 2 Catalytic Subunit


External Links