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You are here:Home » Antibodies » Abs to Protein Kinases » Anti -AMP Activated Protein Kinase alpha2 (AMPK alpha-2 Chain, AMPK Subunit alpha-2, AMPK a2, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-2, AMPK2, PRKAA2, PRKAA)

Anti -AMP Activated Protein Kinase alpha2 (AMPK alpha-2 Chain, AMPK Subunit alpha-2, AMPK
a2, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-2, AMPK2, PRKAA2, PRKAA)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
AMPK2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Catalog #A1475-02M
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
ELISA: 0.25ug/ml
Western Blot: 0.5-2.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide corresponding to the center region of human AMPK2 (KLH).
SpecificityRecognizes human AMPK2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=2.7.11.1, Protein Kinase AMP-activated alpha 2 Catalytic Subunit


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