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You are here:Home » Antibodies » Abs to Protein Kinases » Anti -AMPK, gamma3 (AMP Activated Protein Kinase gamma3, PRKAG3, protein kinase, AMP-activated, gamma 3 non-catalytic subunit, AMPKG3, 5'-AMP-activated protein kinase, gamma-3 Subunit, AMP-activated protein kinase, non-catalytic gamma-3 Subunit)

Anti -AMPK, gamma3 (AMP Activated Protein Kinase gamma3, PRKAG3, protein kinase,
AMP-activated, gamma 3 non-catalytic subunit, AMPKG3, 5'-AMP-activated protein kinase,
gamma-3 Subunit, AMP-activated protein kinase, non-catalytic gamma-3 Subunit)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Catalog #A1475-08F
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:8000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide with sequence C-KLGWDDELRKPGAQ, from the internal region of human AMPK, gamma3.
SpecificityRecognizes human AMPK, gamma3. Species sequence homology: bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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