Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Biochemicals » Biochem-Antibiotics » Amphotericin B (Fungizone, Fungilin, Ampho-Moronal)

Amphotericin B (Fungizone, Fungilin, Ampho-Moronal)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first isolated by Gold, et a., from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B is poorly soluble in water. Amphotericin B binds to sterols, preferentially to the primary fungal cell membrane sterol, ergosterol. This binding disrupts osmotic integrity of the fungal membrane, resulting in leakage of intracellular potassium, magnesium, sugars, and metabolites and then cellular death.
Catalog #A2221
Used in the preparation of baculoviral stocks.
AppearanceYellow to orange, crystalline powder
Identification (FAB/MS)Conforms to reference
SolubilitySoluble in DMSO and DMF/HCl
Amphotericin B is poorly soluble in water.
Potentcy 750ug/mg
Loss on Drying 5.0%
Endotoxin 2Eu/mg
StorageStore at 4°C. Light sensitive.
CAS Number1397-89-3
Molecular FormulaC47H73NO17
Molecular Weight924.09
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesStreptomyces

External Links