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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified E IH

Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer’s disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy-body dementia, Down’s syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
Catalog #	A2275-58T
Applications	Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended dilutions	Immunohistochemistry (Formalin/paraffin): 1:15 for 30 min. Staining of formalin-fixed tissues will be enhanced by pretreatment with 95% formic acid for 5-30 minutes at RT followed by thorough washing in distilled water.
Positive Control	Human brain of Alzheimer’s disease
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone Type	Polyclonal
Host	Rabbit
Source	Human
Concentration	0.1mg/ml
Form	Supplied as a liquid in 10mM PBS, pH 7.6, 0.2% BSA and 15mM sodium azide, before the addition of glycerol to 40%
Purity	Purified by immunoaffinity chromatography.
Immunogen	A synthetic peptide from aa 8-17 of human amyloid beta-protein. Cellular Localization
Specificity	Recognizes Amyloid beta.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.