Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC FC
Alzheimer’s disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (A 4) protein has been found to be the principal constituent of senile plaques of AD’s patients (1-2). The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD A 4 protein. Two variants of A 4 can be detected; A 1-40 “short-tailed” and A 1-42 “long-tailed” (3-4).
Catalog #A2275-58X
ApplicationsSuitable for use in Flow Cytometry, Western Blotting, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:20
Western Blotting: 1:5,000-20,000
Immunohistochemistry: 1:250-500
Immunocytochemistry:1:250-500
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No6k24
HostRabbit
SourceHuman
FormSupplied as a liquid
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in the NPXY motif of human Amyloid Beta A4 precusor (APP)
SpecificityRecognizes human Amyloid Beta A4 precusor (APP)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesA4, AAA, ABETA, ABPP, AD1, Alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), Amyloid beta A4 protein precursor, APPI, Cerebral vascular amyloid peptide, CTFgamma, CVAP, PN2, PN-II, PreA4, Prote


External Links