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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid A4 (Amyloid beta) Variant 40

Anti -Amyloid A4 (Amyloid beta) Variant 40

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (A 4) protein has been found to be the principal constituent of senile plaques of ADs patients (1-2). The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kDa A 4 protein. Two variants of A 4 can be detected; A -40 short-tailed and A -42 long-tailed (3-4).
Catalog #A2275-59F
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500 (5ng)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E136
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in human Beta-amyloid protein 40.
SpecificityRecognizes human Amyloid A4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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