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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid A4, Variant 40, CT (Amyloid beta)

Anti -Amyloid A4, Variant 40, CT (Amyloid beta)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Ab4) protein has been found to be the principal constituent of senile plaques of ADs patients. The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD Ab4 protein. Two variants of Ab4 can be detected; Ab-40 short-tailed and Ab-42 long-tailed.
Catalog #A2275-59F1
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No12K245
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder from 0.01M PBS, pH 7.2. Reconstitute in ddH2O to 1mg/ml.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to the C-terminal (GLMVGGVV) of human beta amyloid peptide 40 (KLH).
SpecificityRecognizes the C-terminal of human beta amyloid peptide 40, and full length beta amyloid peptide 40.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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