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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid Beta, 1-40, 42 (CT) (Amyloid A4)

Anti -Amyloid Beta, 1-40, 42 (CT) (Amyloid A4)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IC
Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Ab4) protein has been found to be the principal constituent of senile plaques of ADs patients. The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD Ab4 protein. Two variants of Ab4 can be detected; Ab-40 short-tailed and Ab-42 long-tailed.
Catalog #A2275-59G
ApplicationsSuitable for use in ELISA, Western Blot, and Immunocytochemistry. Other applications not tested.
Recommended DilutionELISA: 0.05ug/ml
Western Blot: 1ug/ml
Immunocytochemistry: 0.1-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L23
HostMouse
ConcentrationAs reported
FormSupplied as a lyophilized powder in 2X PBS, PEG, sucrose, 0.1% sodium azide. Reconstitute with 1ml dH2O.
PurityPurified by thiophilic adsorption and size exclusion chromatography.
ImmunogenC-terminal peptide (KLH).
SpecificityRecognizes the C-termini of both beta Amyloid 1-40 and 1-42
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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