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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid beta A4 Precursor Protein-Binding, Family B, Member 1 (APBB1, Fe65, MGC:9072, RIR, Adaptor Protein FE65a2, Stat-like Protein)

Anti -Amyloid beta A4 Precursor Protein-Binding, Family B, Member 1 (APBB1, Fe65,
MGC:9072, RIR, Adaptor Protein FE65a2, Stat-like Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.
Catalog #A2275-61P2
Positive Control IMR32 neuronal cell lysate, HEK 293 cell lysate, or brain lysate
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceRat
ConcentrationNot determined
FormPBS, 15% glycerol
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant rat protein expressed in bacteria. Homology: Rat
SpecificitySpecies Crossreactivity: This antibody reacts with the human and mouse proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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