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You are here:Home » Antibodies » Antibodies-Amyloid » Anti -Amyloid A, Serum (Serum Amyloid A, SAA)

Anti -Amyloid A, Serum (Serum Amyloid A, SAA)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
SAA is an acute phase protein and a sensitive inflammatory marker. Cytokines such as IL-1, IL-6 and TNF-alpha stimulates hepatocytes to produce and release SAA. In acute phase, SAA in blood can increase to more than 1,000 folds of normal level.  Prolonged and repeated elevation of SAA results in abnormal deposition of amyloid proteins in organ or tissue in insoluble beta pleated form. Determination of SAA levels is important for assessment of renal allograft rejection, estimation of tissue damage caused by myocardial infarction and severe angina, and diagnosis of inflammation in cystic fibrosis patients and in patients infected with virus.
Catalog #A2275-61Y
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
HybridomaSp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No10g158
Concentration~1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 500ul sterile ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenHighly purified recombinant human SAA (MW: 12 kD).
SpecificityRecognizes natural and recombinant human SAA. Does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, TGF-beta and EGF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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