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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Amyloid precursor protein (APP) and APP-like proteins are transmembrane glycoproteins with a similar modular domain structure.
Catalog #A2275-69B
Comments This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Epitope N-terminal
ApplicationsWestern Blot: (Ab 1ug/ml for 2 hours at RT)
Immunohistology (Formalin/paraffin): (Ab 1:100 for 10 min at RT) Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Positive Control Brain.
Cellular Localization Cytoplasmic and extracellular
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.6, 0.2% BSA and 15mM sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to N-terminal of human APP.
SpecificityRecognizes APP (b-APP770), MW 110kD. Predicted to recognize b-APP695 and b-APP751. Species Crossreactivity: Human, Mouse and Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesA4, AAA, ABETA, ABPP, AD1, Alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), Amyloid beta A4 protein precursor, APPI, Cerebral vascular amyloid peptide, CTFgamma, CVAP, PN2, PN-II, PreA4, Prote


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