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Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)
Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| Amyloid precursor protein (APP) is a type I integral membrane protein with a large N-terminal extracellular domain, a single transmembrane domain, and a short cytoplasmic tail. APP can be sequentially cleaved by beta-secretase and gamma-secretase to release beta-amyloid, which is the main component of senile plaque in patient brains inflicted with Alzheimer's disease. | | | Amyloid Precursor Protein (Ab-730) Polyclonal Antibody is developed in rabbit using the synthesized peptide derived from human APP around the phosphorylation site of serine 730 (Y-T-SP-I-H). | | | Catalog # | A2275-69J | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 0.05-0.2ug/ml | | Western Blot: 0.1-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 30% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthesized peptide derived from human APP around the phosphorylation site of serine 730 (Y-T-SP-I-H). | | Specificity | Recognizes endogenous level of mouse APP. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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