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You are here:Home » Antibodies » Abs to Amyloid » Anti -APBA1 (Amyloid beta A4 Precursor Protein-binding Family A Member 1, Neuron-specific X11 Protein, Neuronal Munc18-1-interacting Protein 1, Mint-1, Adapter Protein X11alpha, X11, MINT1)

Anti -APBA1 (Amyloid beta A4 Precursor Protein-binding Family A Member 1, Neuron-specific
X11 Protein, Neuronal Munc18-1-interacting Protein 1, Mint-1, Adapter Protein X11alpha,
X11, MINT1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
APBA1 is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This protein is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Catalog #A2275-71K1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 0.1-0.3ug/ml, observed in human brain, cerebellum and hippocampus, lysates on ~100kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-EASHPSQDGKRQYK, from human APBA1, at the internal region of the protein (NP_001154.2).
SpecificityRecognizes human APBA1. Species sequence homology: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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