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Anti -APBA1 (Amyloid beta A4 Precursor Protein-binding Family A Member 1, Neuron-specific X11 Protein, Neuronal Munc18-1-interacting Protein 1, Mint-1, Adapter Protein X11alpha, X11, MINT1)
Anti -APBA1 (Amyloid beta A4 Precursor Protein-binding Family A Member 1, Neuron-specific
X11 Protein, Neuronal Munc18-1-interacting Protein 1, Mint-1, Adapter Protein X11alpha,
X11, MINT1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| APBA1 is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This protein is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. | | | Catalog # | A2275-71K1 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:16,000 | | Western Blot: 0.1-0.3ug/ml, observed in human brain, cerebellum and hippocampus, lysates on ~100kD bands | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-EASHPSQDGKRQYK, from human APBA1, at the internal region of the protein (NP_001154.2). | | Specificity | Recognizes human APBA1. Species sequence homology: Mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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