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You are here:Home » Antibodies » Abs to Apoptosis » Anti -Amyloid Precursor Protein, CT (APP, Amyloid beta (A4) Precursor Protein)

Anti -Amyloid Precursor Protein, CT (APP, Amyloid beta (A4) Precursor Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IP IH
APP is a 110-130kD transmembrane protein. Processing of APP by Beta-secretase gives rise to amyloidogenic beta-amyloid proteins, deposition of which are characteristic of Alzheimer disease. APP exists in a number of isoforms. APP(695) is predominant in neuronal tissue, whilst APP(751) dominates elsewhere.
Catalog #A2275-71L
ApplicationsSuitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Other applications have not been tested.
Recommended DilutionImmunohistochemistry: Frozen
Western Blot: 1:500-1:1000
Optimal working dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.02% sodium azide.
PuritySerum
ImmunogenSynthetic peptide from C-terminus of Amyloid Precursor Protein.
SpecificityRecognizes an epitope at the C-terminus of human amyloid precursor protein (APP). Species Crossreactivity: Monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesA4, AAA, ABETA, ABPP, AD1, Alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), Amyloid beta A4 protein precursor, APPI, Cerebral vascular amyloid peptide, CTFgamma, CVAP, PN2, PN-II, PreA4, Prote


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