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You are here:Home » Antibodies » Abs to Apoptosis » Anti -Amyloid Precursor Protein, ox-2 Domain (APP, Amyloid beta (A4) Precursor Protein)

Anti -Amyloid Precursor Protein, ox-2 Domain (APP, Amyloid beta (A4) Precursor Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IP
APP is a 110-130kD transmembrane protein. Processing of APP by beta-secretase gives rise to amyloidogenic beta-amyloid proteins, deposition of which are characteristic of Alzheimer's disease.
Catalog #A2275-71S
APP exists in a number of isoforms, not all of which contain the OX-2 domain.
ApplicationsImmunoprecipitation: Disulphide reduction required
Western Blotting: 1:500-1:1000
Optimal working dilutions to be determined by researcher.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.02% sodium azide.
PuritySerum.
ImmunogenAntisera to human APP were raised by repeated immunizations of rabbits with highly purified antigen.
SpecificityRecognizes an epitope within the OX-2 domain of the human amyloid precursor protein (APP). Species Crossreactivity: Human, monkey
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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