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You are here:Home » Antibodies » Abs to Apoptosis » Anti - -Amyloid (1-42)

Anti - -Amyloid (1-42)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum
Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer’s disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
Catalog #A2275-74Q
Applications Suitable for use in Immunohistochemistry, Western Blot, ELISA. Used in immunohistochemical staining of Alzheimer's disease plaques.
Recommended DilutionImmunohistochemistry: Paraffin. Requires formic acid pre-treatment.
Western Blotting: 1:500-1:1000
Optimal working dilutions to be determined by researcher.
Recommended Secondary Reagents Sheep anti Rabbit IgG (Aff. Pur.): HRP
Recommended Positive Control Tissue: Alzheimer's diease brain
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.02% sodium azide.
PuritySerum
ImmunogenAntisera to Beta amyloid (1-42) were raised by repeated immunizations of rabbits with highly purified antigen.
SpecificityRecognizes the beta amyloid (1-42) peptide that is an important factor in the pathogenesis of Alzheimer's disease.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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