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Specifications

Clone Host Grade Applications Polyclonal Rabbit Purified IH

Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Ab4) protein has been found to be the principal constituent of senile plaques of ADs patients. The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD Ab4 protein. Two variants of Ab4 can be detected; Ab-40 short-tailed and Ab-42 long-tailed.
Catalog #	A2275-75E
Applications	Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution	Immunohistochemistry (paraffin): 1:250-1:500
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone Type	Polyclonal
Host	Rabbit
Source	Rat
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS. No preservative added.
Purity	Purified
Immunogen	Synthetic peptide corresponding to Rat/Mouse Amyloid Beta peptide, aa3-16.
Specificity	Recognizes rat/mouse Amyloid beta. Reacts extremely well with all isoforms. Does not cross-react with human Amyloid beta.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.