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You are here:Home » Antibodies » Abs to Amyloid » Anti - -Amyloid (1-42), CT

Anti - -Amyloid (1-42), CT

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IC
Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer’s disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
Catalog #A2275-75W
ApplicationsSuitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionELISA: 0.05ug/ml
Immunocytochemistry: 0.1-1ug/ml
Western Blot: 1ug/ml for HRP/ECL detection
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6D5
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, PEG, sucrose.
PurityPurified by subsequent thiophilic adsorbtion and size exclusion chromatography.
ImmunogenSynthetic peptide corresponding to aa1-42 of C-terminal human b-amyloid (KLH).
SpecificityRecognizes the C-terminus of human b-amyloid aa1-42 isoform. Does not cross-react with b-amyloid aa1-40 isoform.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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