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You are here:Home » Antibodies » Abs to Amyloid » Anti - -Amyloid (1-42), CT (Biotin)

Anti - -Amyloid (1-42), CT (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IC
Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer’s disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
Catalog #A2275-75W1
Applications
Suitable for use in ELISA, Immunocytochemistry and Western Blot. Other applications have not been tested.
Recommended DilutionsELISA: 0.05ug/ml
Immunocytochemistry: 1-10ug/ml
Western Blot: 1ug/ml Recommended blocking buffer: Casein/Tween-20 based blocking and incubation buffer.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6D5
HostMouse
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS and 0.09% sodium azide, before the addition of glycerol to 40%. Labeled witth Biotin.
PurityPurified by subsequent thiophilic adsorption and size exclusion chromatography.
ImmunogenSynthetic peptide corresponding to aa 1-42 of C-terminal human b-amyloid (KLH).
SpecificityRecognizes the C-terminus of human b-amyloid (aa 1-42 isoform). Does not cross-react with b-amyloid (aa 1-40 isoform).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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