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You are here:Home » Antibodies » Abs to Amyloid » Anti - -Amyloid

Anti - -Amyloid

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IP IH
Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the
brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer’s disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type) and in the Guam
Parkinson-Dementia complex.
Catalog #A2275-78A
ApplicationsSuitable for use in ELISA, Immunohistochemisry and Immunoprecipitation. Not suitable for Western Blot. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Paraffin): Requires protein digestion pre-treatment of paraffin sections using formic acid for 2-3 minutes. (Detects extracellular amyloid beta with senile plaques and vessel amyloid in Alzheimer's disease brain.)
Optimal dilutions to be determined by the researcher.
Recommended Secondary AntibodyI1904-65W: IgG, F(ab’)2 (HRP) Pab RbxMo
I1904-66C: IgG, F(ab’)2, X-Adsorbed (HRP) Pab RbxMo
Recommended Positive Control TissueAlzheimer's disease brain
Recommended Negative ControlsI1904-78R: IgG1 Murine Negative Control
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No3H532
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide consisting of residues 1-17 of the amyloid beta protein.
SpecificityRecognizes the human beta amyloid peptide, which is the major protein component of the amyloid cores in neuritic plaques.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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