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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Amyloid Precursor Protein (APP) is a transmembrane protein and a constituent of neurofibrillary tangles and senile plaques as seen in Alzheimer’s disease. This antibody does not react with APP-like proteins but reacts with deposited APP isoforms in latestage neurofibrillary tangle-bearing neurons, neuritic processes surrounding senile plaques and neurophil threads in grey matter of Alzheimer’s disease brain.
Catalog #A2275-84H
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Paraffin): 1:25-1:50 for 1 hr. at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Alzheimer’s disease brain tissue, Neurofibrillary tangles and senile plaques staining pattern.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgM
Clone No3G12
HostMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenRecombinant fusion protein representing the extracellular region of APP between the Kunitz protease inhibitor domain and the beta-amyloid region.
SpecificityRecognizes Amyloid precursor protein. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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