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Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)
Anti -Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
IH |
|
| Amyloid Precursor Protein (APP) is a transmembrane protein and a constituent of neurofibrillary tangles and senile plaques as seen in Alzheimer’s disease. This antibody does not react with APP-like proteins but reacts with deposited APP isoforms in latestage neurofibrillary tangle-bearing neurons, neuritic processes surrounding senile plaques and neurophil threads in grey matter of Alzheimer’s disease brain. | | | Catalog # | A2275-84H | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Paraffin): 1:25-1:50 for 1 hr. at RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | | | Alzheimer’s disease brain tissue, Neurofibrillary tangles and senile plaques staining pattern. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 3G12 | | Host | Mouse | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O. | | Purity | Supernatant | | Immunogen | Recombinant fusion protein representing the extracellular region of APP between the Kunitz protease inhibitor domain and the beta-amyloid region. | | Specificity | Recognizes Amyloid precursor protein. Species Crossreactivity: Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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