You are here:Home
»
Antibodies
»
Abs to Amyloid
»
Anti -Amyloid Precursor Protein (Amyloid beta (A4) Precursor Protein, APP, ABPP, Amyloid beta A4 Protein, Alzheimer Disease Amyloid A4 Protein Homolog, Amyloidogenic Glycoprotein, AG)
Anti -Amyloid Precursor Protein (Amyloid beta (A4) Precursor Protein, APP, ABPP, Amyloid
beta A4 Protein, Alzheimer Disease Amyloid A4 Protein Homolog, Amyloidogenic Glycoprotein,
AG)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimer's disease (AD) (Kamenetz et al., 2003). The phosphorylation APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD (Liu et al., 2003; Ando et al., 2001). | | | Catalog # | A2275-86B | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Rat brain and hippocampus lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Rat | | Concentration | Not determined | | Form | Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 100ug per ml BSA, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Peptide corresponding to amino acid residues from the C-terminal region of rat APP. | | Specificity | Recognizes rat APP. Species Sequence Homology: canine, human and mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
