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You are here:Home » Antibodies » Abs to Amyloid » Anti - -Amyloid Precursor Protein (695aa)

Anti - -Amyloid Precursor Protein (695aa)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
There are 3 known b-APP proteins (b-APP695, b-APP751, b-APP770). The amyloid b-peptide is thought to be derived from all three precursor proteins. Evidence indicates that b-APP is present in senile plaques, extraneuronal tangles, neurous, satellite glial cells of the dorsal root, enteric and trigerminal ganglia, megakaryocytes, cardiac muscle and the pituitary and adrenal glands.
Catalog #A2275-87E
ApplicationsSuitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry (Frozen and Paraffin-embedded): 5-10ug/ml. Suitable for immunohistochemical staining of alcohol-fixed paraffin-embedded or frozen tissue sections. Other fixatives may also work following formic acid treatment.
Western Blot: 0.5-1.0ug/ml
ELISA: 0.1-0.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No6A6
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide
PurityPurified
ImmunogenRec b-APP695
SpecificityRecognizes human b-amyloid precursor protein (b-APP695) that has a predicted amino acid sequence length of 695. There are 3 known b-APP proteins (b APP695, b APP751, b APP770) thought to be the source of amyloid b-peptide. Recognizes an epitope within the first 200 amino acids in the b-APP amino terminus. This antibody will react with all 3 forms.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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