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You are here:Home » Antibodies » Abs to Amyloid » Anti -Amyloid Precursor Protein (APP) (epitope a)

Anti -Amyloid Precursor Protein (APP) (epitope a)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Amyloid precursor protein (APP) is a cell surface receptor and transmembrane precursor protein that undergoes extensive proteolytic processing by secretases to promote the neurite growth, neuronal adhesion, axonogenesis and transcriptional activation. In Alzheimer's disease, APP is broken down and releases the amyloid- beta-peptide that is found in senile plaques and vessels.
Catalog #A2275-87Z
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide (HMNVQNGKWDSDPSGTKTCI) corresponding to aa44-63 of human APP (APP695 isoform)
SpecificityRecognizes human Amyloid Precursor Protein
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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