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You are here:Home » Molecular Biology » MB-Apoptosis » Amyloid P Component, Recombinant, Human (SAP, APCS, PTX2, mature chain 204aa, chromosome 1q21-23)

Amyloid P Component, Recombinant, Human (SAP, APCS, PTX2, mature chain 204aa, chromosome


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The protein encoded by this gene is a glycoprotein, belonging to the pentaxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Catalog #A2275-88E
DescriptionRecombinant Human APCS produced in E.Coli is a non-glycosylated, polypeptide chain having a molecular weight of 23.5kD. Recombinant Human APCS contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
Applications ELISA MS Western Blotting
StabilityRecombinant APCS although stable at 140C for 1 week, should be stored desiccated below -180C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Molecular Weight23.5kD
SourceE. coli
Purity95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
FormSupplied as a liquid in 10mM Tris, pH 8.0, 0.01% Triton X-100, 0.002% sodium azide and 10mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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