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Amyloid P Component (SAP, APCS, PTX2, mature chain 204aa, chromosome 1q21-23) Recombinant, Human
Amyloid P Component (SAP, APCS, PTX2, mature chain 204aa, chromosome 1q21-23) Recombinant,
Human
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| This protein is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. The gene encoding this protein has multiple polyadenylation sites. | | | Catalog # | A2275-88G | | Primary Sequence (aa) | 223 | | Domain (aa) | Full-length | | Tag/Fusion Partner | T7 Tag | | Applications | Suitable for use in ELISA and Mass Spectrometry. Other applications not tested. | | Quality Control | SDS-PAGE | | Storage and Stability | For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | Important note | This recombinant enzyme has NOT been tested with regard to biological activity. | | Source | Human, recombinant protein expressed in E. coli | | Purity | Highly purified | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 10mM Tris, pH8.0, 0.1% Triton X-100, 10mM DTT, 0.002% sodium azide. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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