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You are here:Home » Antibodies » Abs to Receptors » Anti -Androgen Receptor (AR, AIS, Androgen receptor, DHTR, Dihydrotestosterone Receptor, HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 Group C Member 4, SBMA, SMAX1, TFM)

Anti -Androgen Receptor (AR, AIS, Androgen receptor, DHTR, Dihydrotestosterone Receptor,
HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 Group C Member 4, SBMA, SMAX1, TFM)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E FC
The Androgen Receptor (Androgen R) is a 90kD steroid hormone receptor that is critical for the development and function of the male reproductive system. Androgen R binding to testosterone or 5alpha-dihydrotestosterone (DHT) triggers receptor dimerization followed by translocation to the nucleus where it promotes transcription of androgen responsive genes. Multiple polymorphisms in Androgen R are linked to the development of prostate cancer. The ligand binding domain of human Androgen R (aa661-920) shares 100% aa sequence identity with mouse and rat Androgen R.
Catalog #A2281-01D
ApplicationsSuitable for use in ELISA and Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 25ug/ml, 10ul labels 1-2.5 x 10e5 cells in a total reaction volume < 200ul.
Direct ELISA: 0.5-1ug/ml. The detection limit is ~1ng/well.
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells obtained from a mouse immunized with purified, E. coli-derived, recombinant human Androgen R (aa661-920).
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG2B
Clone No9L802
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenE. coli-derived, recombinant human Androgen R (aa661-920; Accession # P10275).
SpecificityRecognizes human Androgen R.
Species Sequence Homology (100%)Mouse and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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