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Specifications

Clone Host Grade Applications Monoclonal Mouse Purified B IH IC

The androgen receptor (AR) has been localized e.g. in the testis, (Sertoli and Leydig cells), prostate, foreskin epidermis, fibroblasts, breast epithelium, sweat and apocrine glands and hepatocytes. Prostate cancers are very heterogeneous with regard to AR expression, the loss of androgen responsiveness is not paralleled by the loss of AR. Studies on AR distribution might be useful to study the role of AR in related disease processes. Antigen localization is nuclear.
Catalog #	A2281-02C
Applications	Suitable for use in Immunoblot, Immunocytochemistry and Immunohistochemistry (frozen sections and paraffin-embedded tissue after mivrowave pretreatment).
Recommended Dilution	Immunohistochemistry: 1:5-1:10; Dilute immediately before use with PBS.
Positive Control	Testis
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	5F196
Host	Mouse
Concentration	As reported
Form	Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
Purity	Purified IgG
Immunogen	Synthetic peptide.
Specificity	Reactive with a 110kD protein in a lysate from the LNCP cell line.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.