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You are here:Home » Antibodies » Abs to Receptors » Anti -Androgen Receptor (AR)

Anti -Androgen Receptor (AR)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IH IC
The androgen receptor (AR) has been localized e.g. in the testis, (Sertoli and Leydig cells), prostate, foreskin epidermis, fibroblasts, breast epithelium, sweat and apocrine glands and hepatocytes. Prostate cancers are very heterogeneous with regard to AR expression, the loss of androgen responsiveness is not paralleled by the loss of AR. Studies on AR distribution might be useful to study the role of AR in related disease processes. Antigen localization is nuclear.
Catalog #A2281-02C
ApplicationsSuitable for use in Immunoblot, Immunocytochemistry and Immunohistochemistry (frozen sections and paraffin-embedded tissue after mivrowave pretreatment).
Recommended DilutionImmunohistochemistry: 1:5-1:10; Dilute immediately before use with PBS.
Positive ControlTestis
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No5F196
HostMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified IgG
ImmunogenSynthetic peptide.
SpecificityReactive with a 110kD protein in a lysate from the LNCP cell line.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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