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You are here:Home » Antibodies » Abs to Receptors » Anti -Androgen Receptor (AR)

Anti -Androgen Receptor (AR)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B
Androgen receptor (AR) belongs to the steroid hormone nuclear receptor superfamily. It functions as an androgen-dependent transcriptional factor that regulates genes for cell proliferation and differentiation. Upon binding to androgen, the androgen receptor (AR) can translocate into the nucleus and bind to androgen response element(s) to modulate its target genes.
Catalog #A2281-02D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:5000 using ECL. An antibody raised to this peptide region has been shown to recognize the 108-110kD bands in rat ventral prostrate nuclear extracts and LNCap cells (3).
ELISA: 1:10,000-50,000 (Coat 50-100ng of control peptide
(A2281-02K)/well).
Optimal dilutions to be determined by the researcher.
Control PeptideA2281-02K: Androgen Receptor, Rat (AR)
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
PuritySerum
ImmunogenSynthetic peptide consisting of 22aa near the N-terminus of Rat Androgen Receptor.
SpecificityRecognizes rat androgen receptor. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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