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You are here:Home » Antibodies » Abs to Receptors » Anti -Androgen Receptor (AR)

Anti -Androgen Receptor (AR)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in the androgen target genes. AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3).
Catalog #A2281-03
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, 50% glycerol.
PurityPurified by protein A and peptide affinity chromatography.
ImmunogenSynthetic peptide (KLH coupled) corresponding to residues surrounding Ser213 of human androgen receptor.
SpecificityDetects endogenous levels of androgen receptor.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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