Anti -Androgen Receptor (AR, AIS, Dihydrotestosterone Receptor, DHTR, KD, HUMARA, HYSP1, Nuclear Receptor Subfamily 3 Group C Member 4, NR3C4, SBMA, SMAX1, TFM)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Purified |
B IH FC IF |
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| Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in the | | | androgen target genes. AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3). | | | Catalog # | A2281-04A | | Applications | Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunofluorescence (IF-IC): 1:600 | | Flow Cytometry: 1:400 | | Western Blot: 1:2000 Incubate membrane with diluted antibody in 5% nonfat dry milk, 1X | | TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. | | Immunohistochemistry (Paraffin): 1:400 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 11C1017 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, less than 0.02% sodium azide, 50% glycerol. | | Purity | Purified | | Immunogen | Recombinant protein corresponding to residues near the amino terminal region of human androgen receptor. | | Specificity | Recognizes endogenous levels of total androgen receptor. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Androgen Receptor (AR, AIS, Dihydrotestosterone Receptor, DHTR, KD, HUMARA, HYSP1, Nuclear Receptor Subfamily 3 Group C Member 4, NR3C4, SBMA, SMAX1, TFM) |
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